ABSTRACT
To determine whether or not slow coronary flow (SF) depends on hemodynamic variables, we studied 17 patients (15 men, mean age = 47.8 years) with SF at coronariography. Exercise thallium-201 myocardial scintigraphy revealed perfusion abnormalities in 13 (76.4 per cent) patients. We then selected 89 individuais submitted to cinecoronariography for comparison: 15 were normal and 74 had heart disease. The coronary flow velocity was evaluated by the number of heart beats (HB) needed for coronary artery dye filling. The patients in the SF group had normal hemodynamic variables which were significantly different from those of patients with heart disease (P = 0.001). Patients with heart disease needed no more than 4 HB to fill their arteries, in contrast to 6.88 ñ 1.68 (5 to 11) in the SF group (P<0.OOO1). Thus, in our patients with myocardial scintigraphy suggesting ischemia, SF was found to be an event which did not depend on hemodynamic factors.
Subject(s)
Humans , Male , Female , Adult , Middle Aged , Angina Pectoris , Coronary Circulation/physiology , Coronary Disease , Thallium Radioisotopes , Analysis of Variance , Hemodynamics/physiology , Blood Flow Velocity/physiologyABSTRACT
Neste trabalho apresentamos estudos preliminares na pesquisa de parâmetros e/ou métodos que melhoram a sensibiliade e especificidade do teste ergométrico. Adotamos a configuraçäo ortogonal de FRANK de eletrodos para aquisiçäo das projeçöes X, Y e Z do ECG. O índice IND incorpora variaçöes, com exercício, da área do segmento ST-T em relaçäo ao repouso, e é independente da posiçäo do coraçäo na caixa torácica ou volume torácico. Mostra-se que as médias do IND säo estatisticamente diferentes entre os grupos de normais e isquêmicos. empregando-se a Regressäo Logística, foram selecionadas variáveis capazes de diferenciar estes grupos com sensibilidade de 81,3% e especificidade de 91,4%